Abstract

INTRAMUSCULAR DEXMEDITOMIDINE AND MIDAZOLAM AS A PREMEDICATION IN PAEDIATRIC SURGICAL PATIENTS, A DOUBLE BLIND RANDOMIZED CONTROL STUDY

*Dr. Kapurkar Vilas S. MD (Anaesthesiology)

Abstract

Aims and Objective-  To compare between intramuscular Dexmeditomidine and Midazolam as premedication in paediatric surgical an aesthesia.  To compare anxiolysis produced by Dexmeditomidine and Midazolam perioperatively.  To study the post operative recovery by analgesic requirement in patients receiving Dexmeditomidine compared with Midazolam. Materials and Methods: A prospective randomized, double blind study involving 60 children undergoing short procedures was conducted. The patients were divided in to 2 groups each involving 30 patients. One group received Dexmeditomidine 1.5 mg/kg and other received Midazolam 0.05mg/kg IM 45 min preoperatively. The efficacy of sedation was assessed using Ramsay Sedation Score. Results: Hemodynamic parameters between the 2 groups were comparable. All sedation scores were comparable in the Dexmeditomidine and Midazolam group. Only 3 children required postoperative analgesia in Dexmeditomidine group, while 7 children in Midazolam group required postoperative analgesia. Conclusion: Dexmeditomidine facilitates adequate sedation as premedication as compared to Midazolam.

Keywords: Dexmeditomidine and Midazolam.