Abstract

SEROPREVALENCE STUDY OF TOXOPLASMA GONDII, RUBELLA VIRUS AND HUMAN CYTOMEGALO VIRUS INFECTION AMONG BAD OBESTETRIC HISTORY AND PRIMIGRAVIDA PREGNANT WOMEN IN IRAQ

*Noor Al- Huda Ali A. H. Saeed, Ban Talib El-Haboby,Samal H.K. AL-Jaff,Ali I. Alsamawi and 5Liqaa Shakir Khadoom

Abstract

The present study was designed to evaluate toxoplasma gondii, rubella and cytomegalovirus infection among Iraqi pregnant women in relation with their age and the trimester of pregnancy. Venous blood was collected from 180 aborted women from different Iraqi private laboratories during the period between October 2015 until march 2016. The randomly selected serum samples were tested for specific anti toxoplasma gondii, anti rubella and anti CMV antibodies(IgM, IgG). Using a commercial ELISA kit (Human – Germany), the series of 180 patients divided into two groups , 90 pregnant patients that had bad obstetric history and the other 9o pregnant women had primigravid that aborted in different times (1st , 2nd ,and 3rd trimesters of pregnancy. The current results showed that IgM antibody of anti toxoplasma among group II (32.2%)29 out of 90 was higher than group I which was (20%) 18 out of 90 women, whereas, anti rubella IgM among group I was (55.5%)50 out of 90 was higher than group II (45.5%) 41 out of 90 , furthermore, IgM in anti CMV among group I was (51.1%) 46 out of 90, also higher than group II (35.5%) 32 out of 90. While, IgG among group I for both of anti toxoplasma and anti rubella (66.6%), (84.4%) was higher than group II which was (61.1%), (76.6%) respectively, but in anti CMV IgG in group II (87.7%) was higher than group I(74.4%). Anti toxoplasma, anti rubella and anti CMV were 9,25,30 out of 90 in group I and 17, 21, 32 out of 90 in group II. The 180 women with mean ang 29-6 years ranged between (14-45) years consisted of 72 women aged between 14-30 and 108 aged between 31-45 years. The gestational period for. group I were (63.3%, 35.5%, 12.2%) and (67.7%, 30%, 13.3%) for group II in the first, second and third trimester of pregnancy. It could be concluded from this study that seroprevalence of toxoplasma, rubella and CMV infection among pregnant women and the high percentage of infection among those patients who extremely high level of ignorance about the disease so, every pregnant wome should be tested for toxoplasma, rubella, cmv serological status.

Keywords: Toxoplasma gondii, Rubella virus, Cytomegalovirus, Bad obstetric history, primigravida, pregnant women.