SYNTHESIS AND CHARACTERISATION OF 5-((4-(2- METHOXYETHYL) PHENOXY) METHYL-2-CHLOROPYRIDINE
Amit Aher* and Dr. Shobha Borhade
Abstract
Chloropyridine is heterocyclic compound. 2-Chloropyridine is used as
a starting material in the production of the antihistamine drug,
pheniramine, and the antiarrhythmic, disopyramide. 2-Chloro-5-
(chloromethyl)-pyridine reacted with 4(2-Methoxyethyl) Phenol to
formed 5-((4-(2-methoxyethyl) phenoxy) methyl-2-Chloropyridine
with good yield. The structure of the target compounds was confirmed
by 1H NMR, EI-MS.
Keywords: Pyridine, Phenol, NMR, Mass spectra, EI-MS.
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