Abstract

A PRELIMINARY INVESTIGATION ON THE CYTOTOXIC AND ANTIPROLIFERATIVE EFFECT OF RASAKARPOORA KULIGAI (RSK)

Dr. V. Manjari*, M. Murugesan and C. Saravanababu

Abstract

Cancer has long ranked as the most common diseases causing death worldwide in the view of the general public and many health professionals. About 70% of cervical cancers occur in developing countries. In low income countries, it is the most common cause of cancer death. The chemotherapy is the standard method of treatment for cancer patients. Rasa karpoora kuligai is one of the Siddha herbomineral prepation mentioned to treat carcinoma. The effect of Rasa karpoora kuligai against HeLa cell lines analyzed through MTT assay, Trypan blue exclusion assay, Dual staining assay, Nuclear morphological assay, Flowcytometry and Gene expression study. Result of the present study suggested Rasakarpoorakuligai have anti oxidant property and potent anticancer activity against HeLa cell lines.

Keywords: Rasakarpoora kuligai, HeLa cell lines.