Abstract

A REVIEW ON ANTHELMENTIC ACTIVITY OF CITRUS AURANTIFOLIA LINN FRUITS EXTRACT

Nilesh Patil*, R.O. Sonawane and Girish S. Patil

Abstract

Objective: The present study was done with the aim to evaluate the anthelmintic activity of aqueous extracts of fruits Citrus aurantifolia Linn belonging to family Rutaceae. Method: The aqueous extracts of fruits Citrus aurantifolia was tested using adult earthworm Pheritima posthuma against Piperazine citrate (10 mg/ml) and distilled water were included in the assay as standard reference drug and control, respectively. The time to achieve paralysis of the worms was determined. Result: aqueous extracts of fruits Citrus aurantifolia produced a potent anthelminthic activity against the P. posthuma when compared with reference standards (p < 0.001). Conclusion: This study shows aqueous extracts of fruits Citrus aurantifolia has paralytic effect on Indian earthworms.

Keywords: Citrus aurantifolia, Pheretima postuma, Piperazine citrate, Anthelminthic activity.