Abstract

BIOLOGICAL SYNTHESIS OF GOLD NANOPARTICLE FROM VITEX TRIFOLIA MEDICINAL PLANT AND THEIR ANTIMICROBIAL PROPERTIES

*Dr. Shweta Sao and Hemlata Nishad

Abstract

There is an increasing commercial demand for nanoparticles due to their wide applicability in various markets, including medicine, catalysis, electronics, chemistry and energy. In this report, a simple and ecofriendly chemical reaction for the synthesis of gold nanoparticles from Vitex Trifolia(Lamiaceae Family) has been developed. Phytochemical and antibacterial activity of Vitex Trifolia leaf with the help of five different extract like petroleum ether, acetone, ethyl acetate, chloroform and distilled water. In this aqueus leaf extracts conforms the presence of various phytochemicals. To evaluate the antibacterial activities of these aqueous extracts were determined by disc diffusion method. From these five extract ethyl acetate shows strong antimicrobial effect on E.coli, Acenatobactor, Proteus, Staphylococcus, Klebsiella. None of leaf extract no more activity in Pseudomonas. Shade dried leaves of Vitex Trifolia was used for the synthesis of gold nanoparticles. To compare the antimicrobial activity of gold nanoparticles with the different leaf extracts.

Keywords: Phytochemicals, Vitex Trifolia, antibacterial activity, gold nanoparticles E.coli, Acenatobactor, Proteus, Staphylococcus, Klebsiella, Pseudomonas.