Abstract

ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF ISOLATED STIGMASTEROL FROM METHANOL EXTRACT OF ACALYPHA INDICA

G. Venkateshwarlu* and N. L. Gowrishanker

Abstract

Isolated stigmasterol from methanolic solvent extract of acalyphaindica were tested for antidiabetic activity and antioxidant activityusing streptozocin induced diabetic rats compared with standard andDPPH method for antioxidant activity. the results expressed thatstigma sterol has significant protection and maximum reduction inblood glucose was observed in streptozocin induced diabetic rats.inDPPH method maximum antioxidant showing the freeradicalscavenging activity of DPPH .the result of this comprehensive studyreveal that Isolated stigmasterol acalypha indica methanol extractshown stastically significant antidiabetic activity comparison to the standard glibenclamide.

Keywords: Acalypha indica, antidibetic activity, streptozocin induced method, Antioxidant acivity, DPPH method.