Abstract

HERBS IN PERIODONTOLOGY – LOCAL DRUG DELIVERY

Abstract

Gingival diseases are the most prevalent dental conditions affecting the adult population. Periodontal disease may appear in a generalized form or in localized areas and highly organized bacterial populations form the advancing front of periodontal pockets. Local delivery controlled release antimicrobials have some advantages over the systemic route, including the high local drug levels in the periodontal pockets, reducing the adverse effects associated with systemic delivery of antibiotics and the drug compliance issues. Local delivery increase the concentration of antimicrobial agent in the pocket and in the GCF where patient compliance is not required. By means of controlled local delivery of agents in the periodontal pocket, a single administration of a limited volume of such agents can maintain therapeutic concentrations within the crevicular fluid for a longer period of time than any other mode of delivery.

Keywords: Herbs, Local Drug Delivery, Periodontitis