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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

ANTI BREAST CANCER AND STUDIES OF ZINC (II) COMPLEX CONTAINING MIXED LIGANDS SCHIFF BASE (4-BROMO-(2- CARBOXYPHENYL)-PYRIDINE-2-YL ETHYLENE AMINE) AND 1, 10- PHENANTHROLINE

Shrimant V. Rathod*, Smita S. Giri and Onkar A. Lotlikar

Abstract

Zinc(II) tetra fluoro borate Schiff’s base complex has been prepared from 4-bromo-(2-carboxyphenyl)-pyridine-2-yl ethylene amine and 1,10-phenanthroline. We report anti-breast cancer activity and study of Zinc(II) complex of mixed ligands Schiff base, 4-bromo-(2- carboxyphenyl)-pyridine-2-yl ethylene amine and 1,10-phenanthroline. It has been evaluated for anti breast cancer activity against MCF-7 cell line.

Keywords: Schiff Base, 4-Bromo- (2-carboxyphenyl)-pyridine-2- yl ethylene amine, 1,10-Phenanthroline, Zinc(II) complex, Anti Breast Cancer.

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