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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

EFFECTS OF INTRAVENOUS MAGNESIUM SULPHATE ON POSTOPERATIVE ANALGESIA IN PATIENTS UNDERGOING MAJOR ABDOMINAL SURGERIES.

Aabid Hussain Mir(MD), Velayat Nabi Buchh (MD), Farooq Ahmad Ganie(MS,MCh)*, Ajaiz Rasool(MD), Zaffer Iqbal (MD), Abida Yousuf(MD), Rohey Jan (MD)

Abstract

Background and objectives: Magnesium has potential as antinocciceptive molecule. These effects are primarily based on physiological calcium antagonism,. Our aim of this study was to evaluate the effects of Magnesium sulphate on quality and potency of postoperative analgesia, postoperative analgesic requirements in patients undergoing major abdominal surgeries under general anaesthesia. We also evaluated its effect on haemodynamic parameters, urine output, postoperative nausea, vomiting and shivering.

Keywords: postoperative, analgesia, intravenous, magnesium sulphate, pain, intrabdominal, general anaesthesia.

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