Abstract

EVALUATION THE ANTIMICROBIAL ACTIVITY OF FOUR FRACTIONS OF SUDANESE PARMELIA PERLATA LICHEN

*Dr. Asma Abdullah Mohamed Hassabo

Abstract

Parmelia perlata (Parmeliaceae) is a lichen (i.e. symbiotic combination of algae and fungi), which is traditionally used for its medicinal properties. The present study was focused to investigate and validate the traditional uses of Sudanese Parmelia perlata (Shaibah) as antimicrobial and qualitatively analyzed its phytoconstituents. Methanol extract was obtained by maceration, then fractionated to: petroleum ether, ethyl acetate and methanol fractions respectively. The cup-plate agar diffusion method was adopted to assess the antimicrobial activity of the fractions against four strains of bacteria (Staphylococcus aurous, Bacillus subtilus, Escherichia coli, Pseudomonas aeruginosa) and one fungal strain(Candida albicans). All fractions showed good antimicrobial activity against all test strains. The phytochemical screening results was shown the presence of flavonoids and terpenoids which may be responsiple of antimicrobial activity. The obtained results was supported the traditional use of this lichen and Sudanese Parmelia perlata can be beneficial in the solving of drugs resistant pathogens.

Keywords: Antimicrobial – lichens - parmelia perlata – fractions.