Abstract

IN VITRO ANTHELMINTIC ACTIVITY OF SECURIDACA LONGEPEDUNCULATA FRESEN. (POLYGALACEAE) AQUEOUS ROOT BARK EXTRACT AGAINST ASCARIDIA GALLI AND RAILLIETINA ECHINOBOTHRIDA ADULT WORMS FROM GUINEAFOWL (NUMIDA MELEAGRIS)

Almamy Konaté*, Mohamed B. Belemlilga, Adama Kaboré, Aristide Traoré, Kessoum Konaté and Hamidou H. Tamboura

Abstract

Securidaca longepedunculata Fresen. (Polygalaceae) is commonly used in Burkina Faso by traditional herbalists and pastoralists to control gastrointestinal parasites. The aim of this study was to screen the aqueous extract of Securidaca longepedunculata for its anthelmintic properties against tapeworms (Raillietina echinobothrida) and roundworms (Ascardia galli). Various concentrations of the plant extract was tested in this bioassay and different parameters such as determination of time of paralysis and time of death of the worms were recorded. Levamisole and Trenamide were used as reference standard against resp. tapeworms (Raillietina echinobothrida) and roundworms (Ascardia galli) and NaCl solution (0.9%) as zero control. All the extracts exhibited significant anthelmintic activity at highest concentration of 50 mg/mL. For Ascaridia galli, efficacy against adult worms in 12.5 and 25 mg/mL of aqueous extract of Securidaca longepedunculata at 24 h was 29% (p

Keywords: Ascaridia galli, Raillietina echinobothrida, Securidaca longepedunculata, Root extracts.