Abstract

HISTOPATHOLOGICAL STUDY OF THE PATTERNS OF OVARIAN TUMOURS

Harvinder Singh*, Kunda Jagadale, N.S. Mani, M.N. Karandikar and R.C. Nimbargi

Abstract

Background: Ovarian neoplasms are now the leading cause of cancer related deaths in females and accounts for 3% of all neoplasms in females. Histomorphological study is the gold standard to assess the treatment modalities and prognosis of various tumours. This is a retrospective and prospective study which was carried over a period of 5 years from 2012 to 2016 which included 83 cases. Objectives: To document the spectrum of ovarian tumours by histopathological examination and their radiological and clinical correlation and age distribution. Methods: All the specimens were grossed according to standard grossing protocols. Formalin fixed paraffin embedded sections were stained with haematoxylin and eosin and examined microscopically. The medical record files of the patients were referred for clinical details and radiology reports. Results: Out of the 83 cases, 68 (82%) were benign, 15 (18%) were malignant. The most common tumours were surface epithelial tumours 52 (63%) followed by germ cell tumours 26 (31%) and sex cord-stromal tumours 4 (6%). Serous cystadenoma along with mature cystic teratoma being the most common benign tumours and serous cystadenocarcinoma, the most common malignant tumour. Most of the benign tumours were in 2nd and 3rd decade and malignant in 4th and 5th decade. Most common clinical presentations were mass per abdomen and ascites. Most of the radiology reports were suggestive of neoplasm Conclusion: Histopathological examination is the confirmatory modality for ovarian tumours. Most common tumours were surface epithelial tumours, both benign and malignant, seen in 3rd and 4th decade of life. Radiology has less specificity and is therefore inadequate for distinguishing between benign and malignant tumours.

Keywords: Ovarian tumours, benign, malignant, age groups.