Abstract

AMINO ACID GLUTAMIC ACID ITS ANTICANCER PROPERTIES AND PHARMACOLOGY (A REVIEW)

*Nazir Ahmad Wani and Mukhtar Ahmad Wani

Abstract

Glutamine is a derivative of glutamic acid and is formed in the body from glutamic acid and ammonia in an energy requiring reaction catalyzed by glutamine synthase. It also possesses anticancer activity. So the transportation and metabolism of glutamine are also discussed for better understanding the role of glutamic acid. Glutamates are the carboxylate anions and salts of glutamic acid. Here the roles of various enzymes required for the metabolism of glutamates are also discussed.

Keywords: anticancer activity, glutamine synthase, glutamic acid.