Abstract

ANTIBACTERIAL EFFECTS OF ETHANOLIC LEAF EXTRACTS OF BACHANG (MANGIFERA FOETIDA LOUR.) ON STREPTOCOCCUS MUTANS

Lilik Koernia Wahidah, Ahmad Rokiban, Subur Widodo, Dewi Mut Mainah, Yulianty and Mohammad Kanedi*

Abstract

Bachang (Mangifera foetida Lour.) get less attention in scientific studies, so that it is difficult to find literature about the benefits of this mango in the folk medicine practice and contemporary pharmacology. The study was carried out to find out if the leaf extract of M. foetida is potent as antibacterial against Streptococcus mutans, the dental cariescausing bacteria. Seven different solution were prepared for treatments namely aquadest (as negative control), erythromycin (as positive control) and five levels concentration of bachang leaves extract (v/v), ie 20%, 40%, 60%, 80% and 100%. Susceptiblity of the bacteria was assayed by disc diffusion technique with blood agar base. Minimum inhibitory concentration(MIC) and minimum bactericidal concentration (MBC) were determined by a serial dilution technique with nutrient broth media were used. The results showed bachang leaf extracts significantly inhibit the growth of S.mutans with inhibition zones ranging from 13.74 mm to 19.22 mm. At the maximum concentration the effect even the same as erythromycin. With the MIC value of 14%, the extract exhibits bactericidal properties by MBC test.

Keywords: Bachang, Mangifera foetida, wild mango, mangiferin, Streptococcus mutans, antibacterial.