Abstract

PREPARATION, CHARACTERIZATION AND EVALUATION OF NIOSOMES FOR FUTURE TARGETED DRUG DELIVERY SYSTEM

Kumar Praveen, Rana Kumar Nikhleshwer*, Sadaf Saima and Sharma Monika

Abstract

Niosomes the formulation of surfactant vesicles, as a tool improve drug delivery. The scientists working in the area of drug delivery system has improved their interest. Niosomes are non-ionic vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or their lipids. As like liposomes, niosomes can be unilamellar or multilamellar are suitable as carrier of both hydrophilic and lipophilic drug and are able to deliver drug to the target site. Non-toxic, requiring less production cost, stable over a longer period of time in different condition, so over come drawbacks of liposomes present review describe history, all factor affecting niosomes formulation, characterization, stability, evaluation and also their comparison with liposomes this review also given relevant information regarding various application of niosomes in gene delivery, vaccine delivery, anti-cancer drug delivery, etc.

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