Abstract

HYPOGLYCEMIC ACTIVITY OF LEAVES AND CALLUS OF MEMECYLON UMBELLATUM IN ALLOXAN INDUCED DIABETIC RAT MODEL

Anbukkarasi M.* and Dhamotharan R.

Abstract

Diabetes mellitus is a predominant risk factor for the development ofcardiovascular, nephropathy, opthalamic, obesity, hepatic and manymore associated diseases. Many chemical drugs in market has proveneffective in reducing blood glucose levels, but also lead to manydamages due to years for continuous medication. To reduce these sideeffects, the current research concentrates on the ethnobotanicalprototype of using leaves and callus to reduce diabetic levels in thealloxan induced rodent model. The leaves of callus proved veryeffective in reducing blood glucose levels of treatment groups than incomparison to induced diabetic control and vehicle groups. Thus,ethnobotanical approach can pave a new approach in the field of drug discovery.  

Keywords: Callus, Diabetes mellitus, alloxan induced rodent model. Blood glucose levels.