Abstract

TO STUDY THE THERMODYNAMIC PARAMETERS OF SUBSTITUTED THIOCARBAMIDOPHENOL IN 70% MIXED SOLVENTS AT CONSTANT TEMPERATURE BY CONDUCTOMETRIC METHOD.

S.O. Mohod* and D.T. Tayade

Abstract

Recently in laboratory, thermodynamic parameters of 2-pchlorophenyl thiocarbamidophenol [p-CPTCP] and 2-tolyl thiocarbamidophenol [TTCP] have been investigated conductometrically at different concentration in 70% ethanol-water mixed solvent at constant temperature. Conductivity play vital role in drug diffusion. This work hightlight investigation of G,k,μ values. The thermodynamic parameters ΔH,ΔG and ΔS for the ion pair formation determine from the value of ion association constant at constant temperature. This measurement revealed that solvent-solvent, solutesolvent and solute-solute interaction and the effects of various substitutents.

Keywords: Substituted thiocabamidophenol, Dissociation constant, Thermodynamic parameters.