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Abstract

ANTI-ACETYLCHOLINESTERASE ACTIVITY OF EXTRACTS, FRACTIONS AND COMPOUNDS OF NYMPHAEA STELLATA WILLD. LEAVES

M.K. Mohan Maruga Raja, S.H. Mishra and Agilandeswari Devarajan*

Abstract

Regulating the activities of acetylcholinesterase (AChE) has become an important research focus in the treatment of Alzheimer's disease. Nymphaea stellata Willd. (Nymphaeaceae) is a well known medicinal plant traditionally claimed for various uses including narcotic effect, mild sedative, mind-altering property and inflammatory diseases of the brain. Hence, this work was planned to investigate the various extracts, fractions and reported compounds of N. stellata leaves for acetylcholinesterase inhibition activity.

Keywords: ?-sitosterol, ?-carotene, Alzheimer's disease, lupeol.


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