Abstract

CELL VIABILITY STUDIES OF CUBIC GOLD NANOPARTICLES SYNTHESIZED USING THE EXTRACT OF ALTERNANTHERA SESSILIS

M. Jannathul Firdhouse and P. Lalitha*

Abstract

Gold nanoparticles were synthesized using the extract of Alternanthera sessilis under three different conditions. The synthesized gold nanoparticles were characterized by UV-visible spectroscopy, XRD and SEM analysis. The particle size of the nanogold was confirmed by Debye-Scherrer’s equation and SEM analysis. The phytoconstituents present in Alternanthera sessilis was found to act as a good reductant and capping agent. The cell viability testing on MCF-7 cell lines by MTT assay revealed gold nanoparticles to be non-toxic to the array of cells tested. Though not cytotoxic the non-toxic nature of the biogenic gold nanoparticles provides new opportunities for the safe application in molecular imaging and therapy.

Keywords: cubic nanogold, Alternanthera sessilis, XRD, SEM, cell viability.