Abstract

ASSESSMENT OF GLYCOSYLATED HEMOGLOBIN (HBA1C) IN POST RENAL TRANSPLANTATION PATIENTS-KHARTOUM STATESUDAN

Rania Awad Abdallah Karar, Ekram Hamza Mohamed Babiker and Ayman Ali Mohammed Alameen*

Abstract

Background: Abnormal HbA1c and random blood glucose concentrations have been associated with post renal transplantation patients using Tacrolimus. Therefore, our study aimed to find out the relationship between HbA1c and Tacrolimus levels. Methodology: A case control study involving forty post renal transplantation patients and forty control subjects with different ages and gender. The study measuring HbA1c and Tacrolimus concentration in post renal transplantation patients. Result: Forty post renal transplantation patients and forty control subjects were studied. The mean±SD of duration was 2.22±2.39 years and Tacrolimus dose was 6.09±3.17 g/day. There is an elevation in HbA1c and Tacrolimus in post renal transplantation patients. Tacrolimus concentration Mean±SD was 6.71±1.89 g/ml and has no effect (P=0.0675) on HbA1c concentration of patients. Conclusion: The present study showed that there is no significant relationship between elevation of HbA1c and the concentration of Tacrolimus.

Keywords: Glycosylated hemoglobin (HbA1c), D.M, Post kidney transplant, Tacrolimus.