Abstract

PLASMA CALCIUM AND PHOSPHORUS LEVELS AMONG SUDANESE POSTMENOPAUSAL WOMEN IN KHARTOUM STATE

Ahmed Awad Abd Elwahid Basheer and Mariam Abbas Ibrahim*

Abstract

Background: The aging process and hormonal changes during menopause may have effect on the bone metabolism particularly Plasma Calcium and Phosphorus levels. Objective: The Present study aimed to assess the Level of Plasma Calcium and Phosphorus in Sudanese Postmenopausal Women. Material and Methods: This Cross Sectional study was carried out in Khartoum State during the period from February to May 2017, 50 Premenopausal women as control group and 50 postmenopausal women as cases were enrolled in this study. Plasma calcium and phosphorus level were measured by using MINDRAY Bs-200. Results: The results revealed that, plasma calcium level was significantly decreased in postmenopausal women (mean ± SD: 8.43 ± 0.95 mg/dL) as compared to control (mean ± SD: 9.82±0.48 mg/dL) p-value 0.000. Plasma phosphorus, levels showed significant increase in postmenopausal women (mean ± SD: 3.45±0.37 mg/dL) compared to control group (mean ± SD: 3.20±0.31 mg/dL) p-value: 0.000. Calcium levels was positively correlated with age per years of postmenopausal women (R=0.458, P=0.001), while it was inversely correlated with weight of postmenopausal (R=-0.394, P=0.034) phosphorous levels among the postmenopausal women was positively correlated with weight(R=0.320, P=0.024) While it was no correlation with age of postmenopausal women(R=-0.153, P=0.290). Conclusion: The postmenopausal women had low plasma calcium, and high levels of plasma phosphorus. Therefore postmenopausal women at high risk for developing osteoporosis, bone fracture and low bone mineral density than pre-menopausal women.

Keywords: Menopause, Bone metabolism, Calcium, Phosphorus.