Abstract

USE OF URINE CELLULAR DEPOSITS OF FEMALE STUDENTS IN EBONYI STATE UNIVERSITY, AS PREDICTIVE INDEX FOR URINARY TRACT INFECTIONS.

Augustine, Bernadette Ngozi, Okekpa, Simon, Fasogbon, Samuel Ayobami, *Ajileye Ayodeji Blessing

Abstract

Background: Urine cytology is a diagnostic test, normally undertaken in hospitals to look for abnormal cells in urine. The method depends on the fact that the mucosa of the whole urogenital tract undergoes continuous regeneration and that urothelial cells are constantly shaded into and excreted with the urine. Objectives: This research work was carried out to determine the effectiveness of urine cytology in the diagnosis of urinary tract infections in female students from Presco campus, Ebonyi State University, Abakaliki. Materials and Method: Urine specimens were collected randomly from female students of Ebonyi State University (Presco campus). Voided urine samples were collected from 100 females into universal sterile containers and transported to Histopathology/cytopathology laboratory for analysis. Aliquot of each sample was transferred into a clean test tube, centrifuged and sediments used to make smears which were fixed immediately in 95% alcohol. The smears were finally stained using haematoxylin and eosin staining technique. The smears were viewed with a light microscope. Results and Discussions: The result obtained from the photomicrographs of stained voided urine samples from females without any sign of urinary tract infections showed normal urothelial cells. Among those with signs and symptoms of urinary tract infections, the photomicrographs obtained showed abnormal urothelial cells, abnormal cells with irregular nuclear outline and blood cells which are suggestive of urinary tract disorder. The presence of blood cells in voided urine samples (haematuria) confirms urinary tract infection. Conclussion: This shows that urine cylotogy can be an indispensable tool in the diagnosis of urinary tract disorders.

Keywords: Urothelial, Cytology, Haematoxylin, Eosin, Smears.