Abstract

ORAL DISPERSIBLE TABLETS: A REVIEW

Minash Singh Neeraj* and Kumar Hari S.L

Abstract

The need for delivering of drugs to patients efficiently with minimum side effects has prompted pharmaceutical industries to be engaged in the development of new drug delivery systems. Oral route is presently the gold standard in the pharmaceutical industry where it is regarded as the safest, most economical and most convenient method of drug delivery resulting in highest patient compliance. ODT has advantages such as patient compliance, quick onset of action, improved bioavailability, etc. Usually, elderly people experience difficulty in swallowing the conventional dosage forms like tablets, capsules, solutions and suspensions because of tremors of extremities and dysphagia. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets may be difficult. In recent past, several manufacturing technologies such as sublimation technique, spray drying technique etc. are employed to overcome the limitations of conventional tablet dosage forms. Once the mouth dissolving tablets are prepared they are required to be evaluated for various parameters so as to have long term stability and better therapeutic efficacy.

Keywords: Fast Dissolving Tablets, Superdisintegrants, Oral Route.