Abstract

AN INVITRO STUDIES OF CARALLUMA ATTENUATE PHYTOCHEMICALS AS INHIBITORY OF KEY ENZYMES RELEVANT FOR DIABETIC

P. Haripriya, R. Gajalakshmi, M. Durgadevi and A. Chandra Mohan*

Abstract

Medicinal and natural herbal plant products are traditionally used from long time in many countries for the treatment of diabetes mellitus. The present study was designed to testify the potential anti-diabetic activity of flavonoid fraction of Caralluma attenuata by using in-vitro enzyme assay. The results of the invitro α-amylase and α-glucosidase inhibition test displayed that Caralluma attenuata flavonoid fraction had a similar inhibitory effect with that of the standard drug acarbose. Different concentration of flavonoid fraction of Caralluma attenuata showed a remarkable inhibitory activity, compared with the normal control group. To evaluation of invitro antidiabetic activities Caralluma attenuate.

Keywords: Caralluma attenuata, Glucose, yeast cells, ?-amylase and ?-glycosidase.