Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL STUDY OF MEDHYACHURNA–A POLY-HERBAL FORMULATION

Renu Rani*, V.K. Kori, K.S. Patel, Harisha C.R. and Shukla V.J.

Abstract

Cerebral palsy is the second commonest cause for the disability in children, making them physically, mentally and socially handicapped. Cerebral palsy (CP), a static, non-progressive disorder caused by brain insult or injury in the prenatal, perinatal and postnatal time period, is the major developmental disability affecting normally control motor functions. Medhya Churna (MC) is an Anubhoot yoga which is used in many diseases especially in Cerebral Palsy. Till date no information regarding scientific evaluation on Medya churna. So the present study was carried out to standardize the finished product MC to confirm its identity, purity and quality. The presence of Epidermal cells, Colonchyma cells, Starch grains, Covering trichome, Crystal fibers, Pitted vessels, Rhomboidal crystals etc were the characteristic features of observed in microscopy of drug. Physicochemical analysis shows loss on drying 13.05% w/w, water soluble extract is 16.8% w/w and PH is 6.5. High Performance Thin Layer Chromatography (HPTLC) showed 11 spots at 254 and 12 spots at 366 nm. This shows the presence of certain definite constituents in the Churna and is helpful for the easy separation of these constituents.

Keywords: Cerebral Palsy, HPTLC Medhya churna, Pharmacognocy, Pharmaceutics.