Abstract

EVALUATION OF MEMORY ENHANCING ACTIVITY OF ECLIPTA ALBA

Mathew George, Lincy Joseph and *Nimmy Mathew

Abstract

Short and long term memory loss may result from deteriorating cerebral mechanisms due to varied causes which could have a tremendous impact on the quality of life. Herbs are being constantly explored to resolve cognitive deficits. Eclipta alba (Ea) is being examined for its memory enhancing quality as it is traditionally used for this purpose. The shade dried root and stem of Eclipta alba was extracted with distilled ethanol. The suspension of Ea containing 100 and 200 mg/kg was administered to mice to evaluate Transfer Latency (TL) on an elevated plus maze. TL was a measure of acquisition and retrieval learning. The results revealed significant improvement of retrieval memory.

Keywords: Eclipta alba, Transfer latency, bhringaraj.