Abstract

EVALUATION OF ANALGESIC ACTIVITY OF BRUHAT HINGULESHWARA RASA

Shivaleela, Kashinath Hadimur*, R. S. Sarashetti and K. A. Patil

Abstract

Abnormal food habits, style of living, hurry and worry etc. factors disturbs Jatharagni and health, which leads to jwara (fever) & vedana (pain). Bruhat Hinguleshwara Rasa is mentioned in Bhaisajya Ratnavali having a multidimensional therapeutic action i.e. Vedananashak & this activity have encouraged to evaluate the analgesic activity of Bruhat Hinguleshwara Rasa. Albino rats were divided into three groups and distributed 06 in each group. Group-I (Test drug), Group-II (Standard drug) and Group-III (Propylene glycol). Analgesic Activity was tested by Tail Flick method. Significant analgesic activity was observed in Test Drug (GI), and Standard Drug (GII). But in Test Drug (GI) it was highly significant than Control (GIII). In test drug analgesic activity was observed from 0.5thhr to 6thhr while in standard it was from 0.5thhr to 5th hr. Bruhat Hinguleshwara Rasa has shown significant and sustained Analgesic Activity. This study has provided evidence base & given scope for clinical research.

Keywords: Bruhat Hinguleshwara, Rasa, Propylene glycol, Paracetamol, Analgesic activity.