Abstract

SCREENING FOR BIOACTIVE POTENTIAL OF EDIBLE MUSHROOM EXTRACTS AGAINST TOOTH DECAY BACTERIA

Gurusamy Chelladurai* and Venkad Uma

Abstract

The present study aimed to evaluate the antibacterial and anti-mitotic assay of four medicinally important mushroom ethanolic extracts of Pleuroutus sajor-caju, Agaricus bisporus, Calocybe indica and Ganoderma lucidum against Streptococcus mutans isolated from tooth decay using Invitro screening methodology. Among the four mushroom tested, the G. lucidum extract showed maximum inhibitory activity recorded (16 ± 0.58 mm) and the minimum was recorded (10 ± 1.23 mm) in C. indica which was statistically significant (p<0.05). The methanolic extract of G. lucidum showed highest anti-mitotic activity at the concentration of 30 μL with a mitotic index 90.4%. Based on the results, it is concluded that mushrooms extract act as a good antibacterial agent against the bacterial pathogen isolated from tooth decay.

Keywords: Medicinal Mushroom Extracts, S. Mutans, Antibacterial Activity, Anti- Mitotic Activity.