Abstract

PHARMACEUTICAL STANDARDIZATION OF “PARADA MARITA AND VANASPATI JARITA MARITA YASHADA BHASMA” – A COMPARATIVE STUDY

Seetha Chandran*, B. J. Patgiri, Prasanth Bedarkar, Sasikumar Nechiyil, Galib R.

Abstract

Introduction: Yashada bhasma (Calx of Zinc) is a metallic preparation, which is mainly indicated in the management of Prameha (Diabetes), Rajasrava (menorrhagia), Kampavata (Parkinsonism), Netra vikara (Eye disorders) etc. Though previous research works emphasizing on pharmaceutical standardization of Yashada bhasma are available, a comparative pharmaceutical and physico-chemical profile of Yashada bhasma prepared using Parada (Mercury) and Vansapati (Herbal) media is not available till date. Current study was done to establish standard manufacturing procedure (SMP) of Parad marita Yashad bhasma and Vanaspati jarita marita Yashad bhasma and to compare the impact of media on marana based on analytical parameters. Materials and Methods: Raw materials were collected, authenticated and subjected to shodhana purification) procedures. Then Yashada bhasma was prepared by using two different medias in electric muffle furnace as per classical guidelines. Results and Discussion: Parada marita Yashada (PMY) fulfilled classical parameters of bhasma after 7th puta (incineration setup),whereas Vanaspati jarita marita Yashada bhasma (JMY) required 5 putas for the same. Marked variations were observed in the pharmaceutical profiles of samples. Conclusion: To prepare Vanaspati jaritha Yashada Bhasma, five Puta with peak temperature of 5500C was required and for Parada marit Yashada Bhasma, it took seven Puta with peak temperature of 7000C. Jarana makes the Marana process of Yashada easy. The current data on pharmaceutical profile of PMY and JMY may be considered as standard in future studies.

Keywords: Jarana; Marana; Pharmaceutical; Standardisation; Yashada Bhasma; Zinc.