Abstract

PHYTOCHEMICAL AND ISOLATION AND STANDARIZATION OF “SEMECARPUS ANACARDIUM LINN”

*Dr. Vishnu Dutt Singh, Dr. Anil Middha, Dr. Rachna Nimesh and Pavitra Solanki

Abstract

Semecarpus anacardium Linn. (family-Anacardiaceae), commonly called as sanjivani or Bhalltak is well known for its anti-arthritic properties in ayurveda, Traditionally the fruits of this plant are used as carminative, tonic and aphrodisiac, and in the treatment of asthma; leucoderma and nervous debilities. The fruits of Semicarpus anacardium Linn have traditional uses to possess anti-cancer, anti inflammatory, anti-arthritic and anthelmintic activities. Semicarpus anacardium Linn. is acrid, hot and anthelmintic. It is considered beneficial in ascites, tumours and warts, acute rheumatism, Asthma, neuralgia, epilepsy and psoriasis. The juice of the pericarp and also of the tree trunk is powerful counter-irritant and vesicant. the extract material was successively extracted with various solvents such as petroleum ether ethanol and methanol. Thus the obtained extracts were tested for phytochemical analysis which revealed the presence of flavanoids, alkaloids, tannins carbohydrates glycosides and phenolic compounds. Petroleum ether extract showed the phytochemical test for steroids, alkaloids & flavonoids. Ethanolic extract showed the phytochemical test for alkaloids glycosides tannins. Pure toluene yielded two comounds and were labeled as C1 and C2. Petroleum ether: ethyl acetate (95:5) yielded three compounds and were labeled as C3 C4 and C5 respectively. They were characterized by 1H NMR and IR. IR spectra of C1 and C2 compounds exhibited absorption at 349, 2927, 2815, 2723, 2356, 1596, 1353, 767 & 667cm-1 and 3421,2815, 2726, 2356, 1596, 1353, 767and 655 cm-1 respectively. NMR spectrum of C1 and C2 exhibited δ value at singlet-7.2, singlet-3.6, triplet2.3, singlet-2.1, quadrate-1.6, singlet-1.2 & triplet-0.89ppm. and singlet 7.2, triplet-2.3, singlet-2.1, singlet-2.1 &triplet-0.88ppm.

Keywords: Semecarpus anacarduim linn, Phytochemical, Pharmacological, Characterization. Aanalysis.