Abstract

DETERMINATION OF IN VITRO ANTIOXIDANT ACTIVITY OF HYDROCOTYLE JAVANICA THUMB WHOLE PLANT EXTRACTS

Sivakumar V., Michael Evanjaline R. and Ananthi Ravichandrun M.*

Abstract

Antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts of Hydrcotyle javanica whole plant have tested using various antioxidant model systems viz., DPPH, hydroxyl, superoxide and ABTS. Methanol extract of H.javanica is found to possess highest DPPH, hydroxyl and ABTS radical cation scavenging activities. The superoxide radical scavenging activity of H. javanica, ethanol extracts records the highest. Like the antioxidant activity, reducing power of the extract increases with increase in concentration. This study indicates significant free radical scavenging potential of H. javanica whole plant which can be exploited for the treatment of various free radical mediated ailments.

Keywords: Hydroxyl, Flavonoid, DPPH, Methanol.