Abstract

EVALUATION OF WOUND HEALING ACTIVITY OF POLYHERBAL GEL FORMULATION

Amrapali S. Kakade*, R. R. Pagore and K. R. Biyani

Abstract

The aim of present study was Evaluation of Wound Healing activity of Polyherbal Gel Formulation. The different concentration of gel was prepared by using corbopol 940 as a gel base. Azadirachta Indica leaves extract, Tridax procumbens leaves extract, and honey by using partial thickness burn wound model in winster rats. All animals were divided into six groups. Group I was control, Group II was treated by 1% of Azadirachta Indica gel, Group III was treated by 1% of Tridax procumbens gel, Group IV were treated by 1% Honey gel . Group V were treated by polyherbal gel and Group IV were treated by Marketed Preparetion (Reference Standard). For 15 days all gel applied topically. The wound healing activity evaluated by physical parameters namely wound contraction and epithelialization. The polyherbal gel shows significant effect on wound healing activity.

Keywords: Wound healing activity, polyherbal gel, wound contraction and epithelialization.