Abstract

A FT-IR SPECTROSCOPIC STUDY ON HYDROALCOHALIC EXTRACT OF AMALAKYADI-GANA (COMPOUND FORMULATION)

Sadhana Singh, Brijesh Singh*, Aparna Dixit and Vinod Kumar Joshi

Abstract

Fourier transform infrared spectroscopy (FT–IR) technique became applied to recognize the composition, chemical shape and discrimination of bio-molecules in hydroalcohalic extract of Amalakyadi – Gana (compound formulation). 50% hydroalcohalic extract of Amalakyadi – Gana have been scanned in mid infrared vicinity (4000–400cm–1) for IR spectroscopic studies. IR spectra for that reason acquired to discriminating and identifying various functional groups. FT-IR study indicates the presence of flavonoids, tannins, methyl, polysaccharides, and amide groups. Flavonoids have anti inflammatory and antioxidant activity; tannins have anticancer, anti-diarrhoeal activities and improve intestinal disorder. Presence of methyl groups have activity on DNA and switch off to the cancer causing oncogenes. Polysaccharides have immune modulating activity, anticoagulant, hypoglycaemic and antiviral activity. The effects of present study proven the conventional claims made by way of Ayurvedic practitioner. However, the chemical parts accountable for the pharmacological activities stay to be investigated.

Keywords: Amalakyadi –Gana, FT–IR, Flavonoids, Tannins.