Abstract

ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF Barleria acuminata Ness IN ETHANOLIC EXTRACT ON DIFFERENT PATHOGENS

*Karthikeyan, Baskaran and Sebastian Rajasekaran

Abstract

Barleria acuminata Ness belongs to family Acanthaceae. The objective of the present work was to identify the study of antibacterial and antifungal activity of extract of Barleria acuminate. Recently, natural products have been evaluated as sources of antimicrobial and antifungal agents with efficacies against a variety of microorganisms. Present study was designed to evaluate the antibacterial and antifungal activity of Barleria acuminata. The extract was prepared using ethanol. Antimicrobial activity was tested against two gram positive bacteria and gram negative bacteria while antifungal activity was tested against two fungi. Evaluations were based on the zone of inhibition using Agar well diffusion assay. The inhibitory activity was found to be dose dependent. This study represents that ethanol extracts of Leaf, Stem and Root of Barleria acuminata may be utilize as a potential source of antimicrobial and antifungal agents.

Keywords: Barleria acumiata, Antibacterial, Antifungal, Extraction.