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Abstract

DEVELOPMENT AND VALIDATION OF ARTEMETHER & LUMEFANTRINE IN PHARMACEUTICAL DOSAGE FORMS

A. Rajesh* and K. Swapna

Abstract

The developed method was validated for parameters such as System suitability, Precision, Accuracy, Linearity and Robustness for the assay of Artemether + Lumefantrine. Hence the method is suitable, linear, precise, accurate and robust for the assay of Artemether and Lumefantrine. Precision and Accuracy are the major control parameters of the whole validation procedure were within the acceptable limits. The experimental data makes a relevant contribution to the understanding of validation parameters.The present work shows a validated, highly sensitive and selective method for determination of Artemether (20mg) + Lumefantrine (120mg) in tablet dosage forms.

Keywords: Precision , Validation, Dosage Forms


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