DEVELOPMENT AND VALIDATION OF ARTEMETHER & LUMEFANTRINE IN PHARMACEUTICAL DOSAGE FORMS
A. Rajesh* and K. Swapna
Abstract
The developed method was validated for parameters such as System
suitability, Precision, Accuracy, Linearity and Robustness for the assay
of Artemether + Lumefantrine. Hence the method is suitable, linear,
precise, accurate and robust for the assay of Artemether and
Lumefantrine. Precision and Accuracy are the major control
parameters of the whole validation procedure were within the
acceptable limits. The experimental data makes a relevant contribution
to the understanding of validation parameters.The present work shows
a validated, highly sensitive and selective method for determination of
Artemether (20mg) + Lumefantrine (120mg) in tablet dosage forms.
Keywords: Precision , Validation, Dosage Forms
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