Abstract

LIPID PEROXIDATION AND ANTI-OBESITY ACTIVITY OF Nigella Sativa SEEDS

Prasanna srinivasan Ramalingam, Monisha Antony Sagaya Raj, Priyalakshmi Ravichandran, Kumaran Shanmugam, Suganthi Nagarasan, Purushothaman Balakrishnan*

Abstract

Nigella sativa which belongs to the Ranunculaceae family is a traditional medicinal plant used to treat various ailments in earlier days. The seeds of this plant has high potential effect on diseases like cancer and it shows high antioxidant and antilipid activities due to the presence of phytochemical thymoquinone. It also has potent activity against diseases like bronchitis, asthma and skin diseases. The methanol extract of these seeds shows great antibacterial against E.coli and B.subtilis. In the present study, lipid peroxidation and anti-obesity activity of N.sativa seeds was well studied and it can shed more lights on different dimension to the researchers. It also deals with the Quantitative & Qualitative determination of phytochemicals and its pharmacological activities.

Keywords: Nigella sativa, lipid peroxidation, anti-obesity, antioxidant, DPPH, invitro.