Abstract

METAL COMPLEXES OF N-[MORPHOLINE-4-YL-(4- NITROPHENYL)-METHYL]-BENZAMIDE: SYNTHESIS, CHARACTERIZATION AND EVALUATION OF PESTICIDAL AND LARVICIDAL ACTIVITY

S. Kannan* and M. Syed Ali Padusha

Abstract

Inorganic elements play crucial role in biological medical processes and it is evident that many organic compounds used in medicine do not have a purely organic mode of action; some are activated or biotransformed by metal ions metabolism.[1] Chemistry of Mannich bases and their derivatives of metal complexes has become a subject of great interest due to their versatile applications.[2,3,4] The main objective of the present communication is to provide a comprehensive account of Mannich type bases and their chelating behaviour with variety of transition metals such as Co(II), Ni(II), Cu(II) and Zn(II). The new Mannich base ligand, N-[Morpholine-4-yl-(4-nitrophenyl)-methyl]- benzamide, was synthesized from the combination of pnitrobenzaldehyde, morpholine and benzamide. The ligand and its complexes were characterized using various analytical (Chemical tests, Elemental analysis and TLC) and spectral studies (FT-IR, UV-Visible, 1H NMR, and 13C NMR). Further the ligand and its complexes were subjected for their pesticidal and larvicidal activities.

Keywords: Morpholine derivative, Mannich base, metal complexes, pesticidal and larvicidal activities.