Abstract

ANTI-DIABETIC ACTIVITY OF METHANOL EXTRACT OF ROSENVINGEA INTRICATA (J.AG.) BOERGESEN-AN IMPORTANT BROWN SEAWEED

Yuvaraj P. and John Peter Paul J.*

Abstract

The present study was indented to screen the anti-diabetic activity of Rosenvingea intricata (J.Ag.) Boergesen, collected from Idinthakarai, Tirunelveli district, Tamil Nadu, India. The methanolic extract of Rosenvingea intricata (J.Ag.) Boergesen was given via intraperitoneal injection at a dose of 200 and 400mg/kg on alloxan induced Wistar albino rats. The fasting blood glucose level, body weight and the glucose level after the treatment of diabetic rats were measured. The animals treated with 200mg/kg methanolic extract were shown the best result of decrease in blood glucose level at a regular interval when the time increased up to 7h as compared to the dose of 400mg/kg methanolic extract treated animals. The result of the present study expressed that the anti-diabetic activity of the methanol extract was dose dependent.

Keywords: Anti-diabetic, Rosenvingea intricata, Methanolic extract, Wistar albino rats.