Abstract

ANTIMICROBIAL APPLICATION OF SCHIFF’S BASE AND IT’S METAL COMPLEXES: A REVIEW

R. G. Mahale* and Deepak V. Nagarale

Abstract

In last decades Aliphatic, Aromatic and heterocyclic compounds containing one or two heteroatoms are gain attention of researchers knowing importance of Schiff’s base and its application in pharmaceuticals and drug manufacturing as well as in the synthetic compounds of biological interest.[1] Here we reviewed some synthetic methods, Schiff’s base and its complexes formed from condensation of the carbonyls and amines keeping its application regarding biological activity in global prospective. Schiff bases are a popular class of compounds with interesting biological properties. Schiff bases are also versatile metal complexing ligands and have been used to coordinate almost all d-block metals as well as lanthanides and found various application were patented its therapy of Schiff bases.[2]

Keywords: Antimicrobial Activity, Schiff’s Base, Metal Complex, Inorganic preparations, Pharmaceutical.