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Abstract

SYNTHESIS OF 4-(1-PYRROLIDINYL) PIPERIDINE DERIVATIVES AS ANTI-BACTERIAL AND ANTI-FUNGAL AGENTS

Shazia Haider, Zafar Saeed Saify, Nousheen Mushtaq, Mehrun-Nisa Tabinda Z. M1,A.Arain, S.M.Ghufran Saeed, *Seema Ashraf

Abstract

Piperidine and pyrrolidine nucleus containing compounds have tremendous potential to exhibit Anti fungal and antibacterial activity. Considering this different derivatives of 4-(1-pyrrolidinyl) piperidine were synthesized. The identities of the compounds were confirmed on the basis of their spectral data and were screened for their antifungal and antibacterial activity. The compounds 2-5 showed significant and highly significant activity.

Keywords: Piperidine, pyrrolidine , antifungal, antibacterial


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