Abstract

CORRELATION BETWEEN SERUM AND FOLLICULAR FLUID ACTIVIN AND CLINICAL PREGNANCY RATES IN SUBFERTILE WOMEN UNDERGOING INTRACYTOPLASMIC SPERM INJECTION

May Abdul-Kareem, Saad Salih Al-Dujaily* and Mohammad Oda Salman

Abstract

Background: Successful pregnancy requires an intricate succession of molecular and genetic interactions through implantation process. The “window of implantation” or “window of receptivity is a limited time that reciprocal interactions between the embryo and the uterus must be executed within it. Aim of the study: to evaluate the correlation between serum and follicualr fluid activin A and preganancy rates in subfertile women undergoing intracytoplasmic sperm injection(ICSI). Pateints and methods: This study was conducted at the High Institute for Infertility Diagnosis and Assisted Reproductive Techniques, Al- Nahrain University and Kamal Al-Samarayi IVF Center-Ministry of Health in Baghdad-Iraq. The duration of the study extended from November 2015 to September 2016.The study was designed to be prospective cohort study. The sample size was 100 sub-fertile undergoing in ICSI. Serum and follicular fluid activin A were estimated for all women and then the correlation with implantation and pregnancy rates was studied. Results: serum cycle day 2 (CD2) activin A, serum activin A at day of ova pickup (OPU), follicular activin A at day of ova pickup (OPU). All these variables were highly significantly(P

Keywords: Serum Activin A, Subfertile Women, PCOS, ICSI.