Abstract

PROTECTIVE EFFECT OF ETHANOLIC EXTRACT AND FRESH JUICE OF CASSIA AURICULATA LINN. ON THE BLOOD SUGAR OF ALBINO RATS

V. E. Ida Christi*, S. Mohan, Jobinkoshi, Jamsheed M. T., Ashik K. A. and Mohammed Shanoob

Abstract

Diabetes is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin. Lack of insulin affects the metabolism of carbohydrates, proteins, fats and causes significance disturbance of water and electrolyte homeostasis. Lot of plants is available to cure diabetes and also used in traditional system of medicines. Ancient period most of the herbal medicines were used as fresh materials like juice, paste. Later only developed into kashaya then some formulations without proper evaluation of the phytochemicals and proper dosage fixation. Few plants onlyused for the people after evaluation. The aim of study is to evaluate the physiochemical and phytochemical nature of the plant and comparatively study the antidiabetic activity of ethanolic extract and fresh juice of Cassia auriculata Linn. flowerin diabetic rats. Cassia auriculata Linn. commonly known as tanner's cassia, also known as “Avaram” in Tamil language is a shrub belongs to the Caesalpiniaceae family. The flowers are quantitatively evaluated for phytochemical analysis like Flavonoid content, total phenol content etc. and documented. The methanolic extract and fresh juice of the flowers were screened for their protective effect towards reduction in blood sugar level in albino rats by hypoglycemic activity in normal rats and OGTT methods. It shows a very good hypoglycemic activity.

Keywords: Kashaya, hyperglycemia, Avaram, Caesalpiniaceae.