Abstract

PRESCRIBING PATTERN OF ANTI DIABETIC DRUGS AMONG TYPE 2 DIABETES MELLITUS PATIENTS IN NORTH KERALA TERTIARY CARE TEACHING HOSPITAL

Nikitha B.*, Anoop Kumar, Rajeev P. Thomas, Smitha P, Anil Babu A. and Anju T. S.

Abstract

Background: Type 2 Diabetes mellitus is characterized by insulin resistance and progressive β cell failure. To achieve good metabolic control in diabetes and keep long term, a combination of changes in life style and pharmacological treatment are necessary. At present oral and injectable formulations are available, which act by different mechanisms to reduce the blood glucose. The majority of people with diabetes on anti‑diabetic drug therapy. Objective: to determine the prescribing pattern of antidiabetic drug in type 2 Diabetes mellitus. Methods: The prospective observational study was conducted as per protocol approved by IEC. Patient diagnosed with type 2 DM with co-morbidities were selected. Glycemic control was assessed by recording their HbA1c. Descriptive analyses were performed using statistical package for the social science version 20. Results: Based on the study criteria 199 patients were evaluated in the study, including 54.9% male and 45.7% female. Most of the patients were in an age group of 56 to 65 years. The level of HbA1c was found to be higher in 129 patients. A total of 199 prescription were analyzed OHAs were the most common class of drugs prescribed in the study. Sulphonyl urea was used in majority of the population. Glimepiride(11.5%), metformin(9.4%), glybenclamide(1.5%), repaglinide (0.5%), and the least prescribed drug was voglibose.

Keywords: Prescription pattern, T2DM, OHA, HbA1c.