PREPARATION AND EVALUATION OF POLYHERBAL CREAM
Vishin Ashish Patil* and Sachin Annasaheb Nitave
Abstract
Throughout the world, there has been an increasing incidence of
bacterial infections and because of drug resistance and toxicity
associated with long-term treatment with antibacterial drugs, search for
new drugs to treat bacterial infections is ongoing. The aim of the
present study was to formulate polyherbal antibacterial cream and
evaluate its physicochemical properties and stability. To select the best
cream formulation, one general formula of cleansing cream was
considered and then corrected. The best base formula was chosen
according to its monotonousness, straightness and external
attractiveness. The formulation containing the plant extract of Psidium
guajava, Luffa acutangula and Curcuma aromatica was prepared.
Finally, a cream containing stearic acid, triethanolamine, liquid
paraffin, propylene glycol, cetostearyl alcohol, methyl paraben, propyl
paraben and water was chosen as the best formulation. The final
product was a o/w emulsion cream with suitable appearance and desirable physicochemical
stability. Due to the stability of the extract in the cream formulation, it was formulated for
treatment of bacterial skin infections.
Keywords: Psidium guajava, Luffa acutangula, Curcuma aromatica, cream, polyherbal.
[Full Text Article]