Abstract

COMPARATIVE EFFECT OF VITAMINS A AND E ON SPERM MORPHOLOGY OF NICOTINE-TREATED WISTAR RATS

Favour Nyoh Beshel, Augustine Lishilinimye Udefa* and Worthy Imoke Ima

Abstract

This study compared the effect of vitamins A and E on sperm morphology of nicotine-treated rats. Thirty male wistar rats were randomly assigned into six groups (n=5) thus: control received 0.2mL/kg of normal saline; Nicotine (N) group received 1mg/kg of nicotine; Vit A group received 1μg/kg of vitamin A; Vit E group received 50mg/kg of vitamin E; N+Vit A group received both nicotine and vitamin A and N+Vit E group received both nicotine and vitamin E. All groups had access to rat feed and water throughout the study period (3 weeks treatment period and 1 week acclimatization period). Semen were collected for evaluation of sperm morphology. Total sperm defect was significantly increased (p

Keywords: Morphology; Nicotine; Sperm; Vitamin A; Vitamin E.