Abstract

MAGNETIC MICROSPHERES AS SITE SPECIFIC NOVEL DRUG DELIVERY SYSTEM: A REVIEW

*Himangshu Deka, Dr. Bipul Nath and Jiban Debnath

Abstract

The objective of this review on magnetic microspheres is to collect a new architecture that shows a great potential for future tests in the treatment of gastric ulcers. Magnetic carriers receive magnetic responses to a magnetic field from incorporated materials that are used for magnetic microspheres are chitosan, dextran etc. This review covers various reports on magnetic microspheres which can be prepared from a variety of carrier material. In the recent years, there has been keen interest in the development of magnetically target drug delivery system, because they aim to deliver the drug at a rate directed by the needs of the body during the period of treatment and target the activity entity to the site of action. Magnetic microsphere is a one of the newer approach of targeted drug delivery. It involves the use of particulate carriers to a localized diseased site. Site specific drug delivery enhances the efficiency of drug delivery and to reduce toxicity & side effects. The main objectives of this review are to highlight some important aspects of magnetic microspheres as a novel drug delivery system. The review shall cover definitions, concepts, types, mechanism of targeting, evaluation and characteristics of magnetic microspheres as well as various methods and techniques used in their preparations. The review also entails various applications and future prospects of magnetic microspheres.

Keywords: Site specific delivery, magnetite, magnetic microsphere, approaches, magnetic delivery, anti-ulcer agents.