Abstract

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITIES OF CO(II), NI(II) AND CU(II) METAL COMPLEXES OF THE PYRAZOLE DERIVATIVES AS LIGANDS

Ambika Bhusanage and Nirdosh Patil*

Abstract

The Co(II), Ni(II) and Cu(II) metal complexes has synthesized by 2-(4, 5dihydro-1, 5-diphenyl-1H-pyrazol-3-yl) phenol (HL1), 2-(4, 5- dihydro-5-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-3-yl) phenol(HL2) and 2-(5-(4-chlorophenyl)-4, 5-dihydro-1-phenyl-1H-pyrazol-3-yl) phenol (HL3). These complexes were characterized by elemental analyses, conductance measurement, magnetic susceptibility measurement, IR, 1HNMR, ESR, and electronic spectral studies. On the basis of elemental analyses, magnetic and spectral studies octahedral geometry was assigned for these complexes. The complexes have been screened in vitro for their possible antimicrobial activity.

Keywords: Complexes, conductance, magnetic, antimicrobial, pyrazoline.