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Abstract

TOXOPLASMOSIS: IN CATS AND HUMAN

Kirti Dahigaonkar*, Arva Poonawala, Kirti Yelpure, Sreelakshmi Menon, Jaspal Kaur Oberoi and Pratibha Jadhav

Abstract

Toxoplasma gondii is a zoonotic protozoan parasite of warm-blooded animals that has a worldwide distribution. Felids are the only known definitive hosts for T. gondii and a recently infected cat can disseminate hundreds of millions T. gondii oocysts into the environment. When the parasite infects the rodent brain it removes the rat’s innate fear of cats by gaining control over it’s nervous system. Once in the environment, T. gondii oocysts can remain infectious for months or years under favourable conditions which can spread the infection to humans.. Toxoplasmosis is a significant public health concern and an issue of substantial importance to wildlife conservation, so the environmental transport and fate of T. gondiioocysts is an area of considerable scientific interest. Toxoplasma gondii is a ubiquitous protozoan parasite that can infect a wide range of animals including humans. gondii is the single known species of genus Toxoplasma and is considered as one of the most successful eukaryotic pathogens which is of major medical and veterinary importance. Effective vaccines may contribute towards preventing and controlling the spread of toxoplasmosis worldwide. Toxoplasma infection is highly prevalent throughout the world and causes disease in diverse populations. Effective treatment are available for each clinical entity of Toxoplasma, but problems of incomplete clinical efficacy, drug potency, drug safety and length of treatment remain. No well-controlled clinical trials in humans have been performed to evaluate the efficacy and safety of treatment.

Keywords: toxoplasmosis, cats, human, Toxoplasma gondii.


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