Abstract

FORMULATION AND EVALUATION OF FAST DISINTEGRATING TABLETS OF VALSARTAN BY USING BANANA POWDER AS DISINTEGRATING AGENT

T. Praveen Kumar* and C. Soujanya

Abstract

The aim is to formulate various batches of Fast disintegrating tablets of Valsartan by using Banana powder and SSG with different concentrations 2%, 4%, 6%, individually by using different diluents like Mannitol and Microcrystalline cellulose by direct compression method. The tablets were evaluated for the precompression parameters such as bulk density, compressibility, angle of repose etc and post compression parameters like hardness, weight variation, friability, disintegration time and in-vitro dissolution profiles. Tablets containing banana powder as disintegrating agent were dispersed rapidly within 35 sec and showed 98.5% drug release in 30 min.

Keywords: Fast disintegrating Tablet, Valsartan, Banana powder.